Retatrutide (LY3437943) is a triple agonist peptide of glucagon receptor (GCGR), glucose-dependent insulinotropic peptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds to human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. Retatrutide could be used in obesity research.
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Retatrutide (LY3437943) is a triple agonist peptide of glucagon receptor (GCGR), glucose-dependent insulinotropic peptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds to human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. Retatrutide could be used in obesity research.